Aim: 
                              The study was carried out to investigate the 
                              prevalence and antimicrobial susceptibility of 
                              clinical pathogens isolated from Bovine Mastitis 
                              in and around Coimbatore District, Tamilnadu, 
                              South India. 
              
                               Materials and Methods: A total 
                              of 250 milk samples were screened and 152 isolates 
                              of Staphylococci were obtained and their 
                              susceptibility to several antimicrobial agents by 
                              agar disc diffusion method. 
              
                               Results: Out of 
                              152 isolates of Staphylococcus aureus resistance 
                              was detected in 63 (41.44%), 39 (25.65%), 
                              21(13.81%), 18 (11.84%), 6 (3.94%) and 5 (3.28%) 
                              isolates for penicillin, streptomycin, 
                              erythromycin, tetracycline, ampicillin and 
                              Cephalothin, respectively. No resistance was 
                              detected for Gentamicin. 
              
                               Conclusion: 
                              Results indicated that these isolates exhibited 
                              the highest degree of resistance to penicillin of 
                              all antimicrobial agents tested. 
              
                               Keywords: 
                              Antimicrobial agents, Bovine Mastitis, Disc 
                              diffusion, Mastitis pathogens